Personalized medicine

The session

Technologies to provide a human care

“A good physician treats the disease; the great physician treats the person who has the disease. One needs to construct the patient's story. And it is this story that allows making the correct diagnosis and treatment.” It is with these words that Sir William Osler, around 1870, might have first posed the challenge of an integrated approach around the patient that has later become a personalized medicine approach. Roughly 150 years after Sir William Ossler’s vision, TechMed is making a decisive step forward to becoming one of Europe’s key players in the domain of personalized medicine, thereby shaping society to fulfil this visionary physician’s quest.

Predictive, Preventive, Personalized, and Participatory medicine, or Personalized Medicine, in short, is that specific stream in medicine that considers each patient’s unique characteristics leading to a targeted health and care approach specific to the individual person. But while the term “medicine” indicates that this form of healthcare is only related to drugs, personalized medicine also sees a technological drive and will induce a transformation of how health and well-being are approached, and medicine is being implemented. With the broadening of Personalized Medicine, many new possibilities are opening up, that should be tackled, and the full potential of the use of new technologies for Personalized Medicine should be unlocked.

Where & When
  • Time: 10.15 - 12.00
  • Language: English
  • Room: INNOVATION ROOM (TL1133)
  • Seats: 100

Speakers & Moderators

Prof.dr. Sabine Siesling
University of Twente & IKNL

Prof.dr. Srirang Manohar
University of Twente

Prof.dr. Vera Barbosa Araujo Soares Sniehotta - University of Twente

Prof.dr. Dimitrios Stamatialis
University of Twente

Dr. Erik Groot Jebbink
University of Twente

Dr. Anneliene Jonker 
TechMed Centre

Dr. Jouke Tamsma
TechMed Centre

Dr. Marco Caballo

Prof. Dr. Charalampos Tsoumpas

The programme

In this session as such, we will show how technologies can provide personalized care for patients, providing four examples. The first example will focus on technologies for women’s health and how these can be used, optimized, and personalized for women’s health, throughout their lifespan. The second example will investigate renal health, and how technologies will provide better care for patients with renal disease. Are ideas such as artificial kidneys a long-term vision or will they become reality sooner than we expect them to? Thirdly, with the rise of chronic diseases, we need to ensure that we start tackling diseases before they even occur. We will discuss the role of diabetes, and how technology will make a decisive step to returning diabetes. We will close the session by discussing the need for realistic digital and physical models of body parts and organs, for optimizing and standardizing imaging technologies and approaches for personalized health well before their use on patients, so as to accelerate the clinical translation of these advances.

10.15 - 10.25

Welcome & introduction Personalized medicine 
Dr. Anneliene Jonker & Dr. Jouke Tamsma - TechMed Centre

10.25 - 10.45

Technologies for Women's health
Prof.Sabine Siesling - University of Twente and Netherlands Comprehensive Cancer Organisation (IKNL) Nienke Bosschaart - University of Twente
Prof.dr. Lioe-Fee de Geus-Oei - University of Twente (video) Severine le Gac - University of Twente
Dr. Frank Simonis - University of Twente (video)

  • Abstract


    Women’s Health is gaining in attention as a focal point in international research. The need for women’s health to become a central point in healthcare research has been emphasized over the last decade by organizations such as the European Commission and United Nations. At the University of Twente we focus on gaining fundamental knowledge of the (changes in) physical and mental health, including anatomy, physiology and pathology of the female body and wellbeing throughout a lifespan. This includes prevention, health behaviour and treatment of diseases that occur only or mainly in women, such as gynaecological diseases, breast cancer, ovarian cancer and osteoporosis. The research can also seek better understanding of why differences between men and women occur in both health, disease manifestation, and response to treatment. Questions regarding design and uptake of (health) technology for women will be addressed at the University of Twente.

  • Biography - Sabine Siesling

    Sabine Siesling, clinical epidemiologist, studied Biomedical Science at the Leiden University.  She is professor ‘Outcomes Research and Personalized cancer care’ at the department of Health Technology and Services Research, University of Twente and  senior researcher at the Netherlands Comprehensive Cancer Organisation (IKNL). She focusses on the effect of interventions, such as care pathways or implementation of new technologies, on the quality, organisation and outcome of cancer care. The influence of gender and tailored follow-up using/developing prediction models is studied. She has been president of the Netherlands Epidemiological Society (2015-2017) and involved in the International Association of Cancer Registries, NABON Breast cancer audit, and the European Initiative on Breast cancer Care-Quality assurance Development group. She is chair of the Women’s Health pillar of het program ‘Key Enabling Technologies for Personalized Medicine’ of the Technical Medical Centre.

10.45 - 11.05

Technologies fo Renal Health
Prof.dr. Dimitrios Stamatialis - University of Twente

  • Abstract & Biography


    Dimitrios Stamatialis leader of the Advanced Organ Bioengineering and Therapeutics group and member of the MT of the TechMed center of the University of Twente. He also has a part time position at the nephrology department of the Radboud UMC.

    He has long experience in research and education of biomedical membranes and (bio)artificial organs. He is author of more than 165 scientific publications, two books and inventor of 10 patents. Prof. Stamatialis is also board member of European society for artificial organs (ESAO); of the international federation of artificial organs (IFAO); chairman of the working group on bioartificial organs of ESAO; member of the EUTox group, an ESAO working group dealing with research on uremic toxins; section editor of the of the “international journal of artificial organs” and of the “artificial organs” journals.

11.10 - 11.30 

Personalisation of care: the case of Diabetes
Prof.dr. Vera Barbosa Araujo Soares Sniehotta - University of Twente

  • Abstract & Biography


    The systematic development of interventions to change health behaviours that are crucial to manage diabetes is a key priority area. Current technological advances can support the development of interventions that are personalised to individual needs. The University of Twente and partners (like the MST and the ZGT) have a wealth of experience on this area. This presentation will focus on the need to further develop personalised interventions for those living with Type 2 Diabetes and will present some developments thus far as well as a roadmap for the future.


    VAS completed her studies at the University of Minho in Portugal where she worked as an academic and a clinician. In 2006 she moved to Aberdeen as Senior Research Fellow in the Scottish Alliance for Self-Care Research before moving to the University of Newcastle in 2010 to a research Institute on Health and Society and then to the Netherlands to Health Technology and Services Research at BMS in 2020. Her research targets the development and assessment of evidence-based interventions for the promotion of health behaviours and the prevention and self-management of chronic conditions. Her research aims to apply behavioural science to the pursuit of the health of the planet and the health of the population. She has published in leading international journals including the BMJ, Diabetologia, Pain, Health Psychology and Health Psychology Review ( She is passionate about translating behavioural theory and empirical evidence into practice and by doing so, exerting impact.

11.30 - 11.50

A vision of a Super-Phantom Research Infrastructure Centre (sPRICE)
Prof.dr. Srirang Manohar - University of Twente

  • Abstract & Biography


    I will discuss the necessity for a new class of phantoms that mimic, the physical, functional, and physiological features of tissues, organs, and systems. This will enable imaging technologies to be tested and challenged at very early stages of development. I will further discuss a collective vision of the Tech Med Centre and partners at the Amsterdam UMCs, Radboud UMC, and UMC Groningen to propose the first Super-Phantom Research Infrastructure Centre (sPRICE). This national Centre would bring under one roof the means and methods for developing, characterizing, validating, and applying these surrogates of living tissues.


    Srirang Manohar is Professor and Chair, Multi-Modality Medical Imaging (M3I). He works in technology development in photoacoustic and ultrasound imaging, all the way through to early clinical assessment. The intended applications of the technologies are dominantly in the breast and thyroid for non-invasive imaging. In minimally-invasive imaging he leads projects for instrumentation intended for image guidance of interventions in the liver and brain.

The Need for Radioactive Super Phantoms
Prof. Dr. Charalampos Tsoumpas - UMCG

  • Abstract & Biography


    Dr. Charalampos (Harry) Tsoumpas is Full Professor in Quantification in Molecular Diagnostics and Radionuclide Therapy, at the Department of Nuclear Medicine and Molecular Imaging, at the UMCG. His primary research interests revolve around quantitative positron emission tomography across different clinical applications. He is a Fellow of the Institute of Physics (IOP) and of the Institute of Physics and Engineering in Medicine (IPEM) and Senior Member of IEEE.

Liver Twin, the ex-vivo imaging platform
Dr. Erik Groot Jebbink

  • Abstract & Biography


    Erik Groot Jebbink (1987) received his B.S. (2009), M.S. (2013) and PhD (2017) from the University of Twente, Enschede, The Netherlands. He is currently assistant professor at the M3i group, University of Twente and Technical Physician at the department of Vascular Surgery at the Rijnstate hospital, Arnhem. His research interests focus on the interaction between blood flow and stents, based on in vitro and in vivo measurements. He received a NWO-ZonMW-VENI personal grant in 2020

Digital phantoms for 4D breast x-ray CT
Dr. Marco Caballo - Radboudumc

  • Abstract & Biography


    Dr. Marco Caballo is a postdoctoral researcher at the department of Medical Imaging at the Radboud University Medical Center in Nijmegen. His research mainly focuses on the development of Artificial Intelligence algorithms for precision medicine in breast cancer imaging, and on the development of breast phantoms intended for the optimization of x-ray-based perfusion imaging modalities.

11.50 - 12.00

Wrap up & Closing
Dr. Anneliene Jonker & Dr. Jouke Tamsma - TechMed Centre