TOPFIT ICMS - Movement disorders

Abstract

ICMS (Interdisciplinary Consortium for Clinical Movement Sciences & Technology) is a unique partnership for the Netherlands between science, clinic, patients and industry that conducts and coordinates research for care innovation in the field of disorders of posture and movement.

Sint Maartenskliniek, Radboudumc, University of Twente and Roessingh Research & Development/ Roessingh Rehabilitation Centre have combined their research and innovation strengths in this field, resulting in more than 200 researchers and clinicians working intensively together with patients in Nijmegen and Enschede in three research programmes focusing on home monitoring, remote care, personalised surgery, innovative early diagnostics and pharmacology. During this introduction, a brief summary of ICMS' objectives and activities will be given. ICMS; science in motion!

Biography

Prof. J.S. (Hans) Rietman MD, PhD is physiatrist and professor in Rehabilitation Medicine & Technology at the faculty of Engineering Technology University of Twente, the Netherlands. He performs his clinical work as a rehabilitation physician at Roessingh Center for Rehabilitation. From 2014 till 2020 he was president of the Netherlands Society of Rehabilitation Medicine (NSRM).

His research focuses on the clinical use of technology in restoration of functions in patients with neurological disorders and patients with amputations of upper and lower extremities. Since 2018 he is leader of the national program Innovative Medical Devices Initiative (IMDI). Since 2019 he chairs the Mission team Mission 2 (transfer of healthcare to the living environment of people) from topsector Life Science and Health. Since 2021 he is clinical research lead and chair of the eexecutive Committee of the interdisciplinary consortium of movement disorders and technologies ICMS.

Abstract

Dreaming about the future is difficult for a young patient like me who suffers from osteo arthritis. My name is Sandra Ahoud, I am 48 years old. At the age of 40 I was diagnosed with osteo arthritis in my hands. Since the diagnosis more and more joints are affected. Now almost all my joints are affected. Not only the pain dominates, but also the fatigue and giving up of my independence. Research is important for my future. I want to dream again.

Abstract

Combatting rheumatic diseases such as osteoarthritis requires revolutionary breakthroughs that we need to work on together. Therefore, ReumaNederland has, in co-creation with researchers, healthcare professionals, patients, industry and government, developed a roadmap to guide research and innovation in healthcare towards solutions with maximum impact.

Our roadmap is focused on two moon shots:

1. We make rheumatic diseases non-chronic disorders in 2040
2. We realize precision (personalised) care for people with rheumatism (in four areas: prevention, prediction, personalization and participation) in 2040

For osteoarthritis, ReumaNederland has taken the initiative to build a national alliance of parties that are committed to realise these moon shots together. By connecting parties and strengthening collaboration we aim to start a coordinated and sustained offensive against osteoarthritis, to develop innovations that are brought to application faster and best meet societal needs.

Biography

Sevgi Fruytier works as program coordinator at ReumaNederland (Dutch Arthritis Foundation), a patient organisation and healthcare foundation. People with rheumatism, doctors, researchers; politics, healthcare and business - ReumaNederland gets them moving with one goal: a world where rheumatic diseases are no longer chronic, but reversible and curable. ReumaNederland connects people, finances, gives direction and advocates for the needs of people with rheumatism.

Sevgi’s work focuses on strengthening collaboration between parties in the field of osteoarthritis. By building a national osteoarthritis alliance ReumaNederland aims to guide innovation towards maximum impact for people with osteoarthritis.

Previously, Sevgi worked at biotech company Amylon Therapeutics and at the Athena Institute part of the VU University on dialogue and co-creation between patients and other stakeholders in healthcare innovation. She has a background in Biomedical Sciences and Global Health.

Abstract

Knee replacement is a very common intervention for patients with damaged, degraded, or nonexistent cartilage at the knee. The rehabilitation after such intervention can be lengthy, focused on regaining range of motion, adopting a new but correct movement pattern, increasing muscle strength, and ultimately moving pain freely.

Movella and the Sports Surgery Clinic in Dublin are currently working together on a project to facilitate the management of this rehabilitation protocol. First, create methodologies to objectify the assessments performed at the clinic by the physiotherapists. Second, to merge the different data acquired with multiple systems, the subjective data provided by the patients, and the medical indications from the practitioners. Finally, we aim to develop intelligent algorithms that can provide meaningful information to improve decision-making and track patient progress.

Biography

Maria João Cabral received her MSc degree in Biomedical Engineering from the University of Twente, during graduation she focused on neuromotor control. She joined Movella, 3 years ago as a product specialist providing technical support to customers in Europe, Africa, and the Middle East in the areas of health, sports science, and ergonomics. After 1 year she moved to the Solutions team which develops custom-made prototypes together with customers/partners that explore new directions for our commercialized products. Here she tries to match and translate the requirements of health and/or sports institutions into biomechanical and technical specifications that can be achieved with Movella's motion capture technology.

Abstract

In current clinical practice, 3D motion analysis is an important tool to assess patients' gait patterns and guide clinical decision-making. It provides objective data on individual gait patterns and the effects of treatments aimed at improving gait. However, regular 3D motion analysis is laboratory-bound, very expensive and labour-intensive. Wearable sensors are cheap and easy to apply within a limited time. Wearable sensors therefore not only have the potential to replace expensive 3D optoelectronic equipment in conventional gaitlaboratories, but also offer the possibility to assess individuals outside the lab during therapy or in their natural environment.

Biography

Prof. Jaap Buurke, PT, PhD, received his PhD in 2005 from the University of Twente for his work on recovery of gait after stroke. His research at Roessingh Research and Development focuses on human movement analysis with specific expertise in kinesiology (neuromuscular control and biomechanics). He holds the chair of Technology supported human movement analysis at the University of Twente (Faculty of Electrical Engineering, Mathematics & Computer Science, Biomedical Signals and Systems group) Enschede, the Netherlands, is adjunct professor at North Western University Chicago (USA), senior researcher at Roessingh Center For Rehabilitation and a member of the Dutch expert group on Neurorehabilitation. He is actively involved in a diversity of (inter)national projects focusing on motor control, movement analysis, rehabilitation robotics and active assistive devices.

Abstract

Although osteoarthritis (OA) is one of the main contributors to pain and disability worldwide , there are no pharmacotherapeutic interventions which can slow disease progression. Consequently current treatment only consists of analgesics. Yet, the outcomes are suboptimal, and a large proportion of OA patients progresses towards end-stage disease when joint replacement therapy is considered. This results in an enormous unmet need towards innovative pharmacological treatments.

Technology can (1) help to find this new (personalized) pharmacological treatments (e.g. with joint om a chip and in-vitro assays), (2) help to assess the effectiveness of the new pharmacological interventions (e.g. with wearables) and, last but not least (3) ensure that new treatments are really used by the patients (e.g. by monitoring medication adherence and empowering patients).

Biography

Bart van den Bemt is clinical pharmacist/ pharmacologist and senior clinical scientist at the departments of Pharmacy in the Sint Maartenskliniek and the Radboudumc in Nijmegen, The Netherlands. Besides that, is Bart also medical manager of the pharmacy department of the Sint Maartenskliniek and manager of Research and Innovation of the same hospital.

Due to his experiences as practicing pharmacist and as senior scientist Bart easily integrates daily patient care of patients with movement disorders in applied research and teaching. Bart is member of several committees/boards on pharmacotherapy, education, pharmaceutical care and rheumatology. Bart was president of the European Society of Clinical Pharmacy and vice-president of the Dutch Association of Hospital Pharmacy.

Bart’s research interests are focused on Personalized Pharmaceutical Care with a focus on movement disorders including medication adherence.